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Will the origin of the COVID-19 pandemic remain a mystery?

The search for the original source of the virus of the Covid-19 pandemic is going on for three years. Although researchers have found 12 close virus ancestors by comparing genomes, they have also found that different parts of the virus are related to ancestors of different times and its direct ancestor can be traced. seems impossible now

At this time it can be said that the time of farewell to the world of the Covid-19 pandemic is near. The countries of the world are focused on bringing their economy back on track. Even in the last three years, the attention of the people along with the scientists was more on whether any new variant of Sarskov-2 (SARS-CoV-2) has come and if it has come then how dangerous it can be. But the reality is that along with this the scientists of the world were also searching that what is the original source of this virus. (Representational photo: Shutterstock)

For the last three years, scientists around the world are struggling with this discovery and trying to find out the exact sequence of ancestors of SARS Cove-2 (SARS-CoV-2). Through this, they want to know what was the original source of this virus. This can help in preventing any other kind of Pandemic in the future. So far scientists have isolated more than a dozen SARS-CoV-2-related viruses from bats and pangolins. (Representational photo: Shutterstock)

The genome of SARS Cove-2 (SARS-CoV-2) is about 30 thousand nucleotides long. On comparing them, experts found that the closest relative of the SARS Cove-2 virus was the bat BANAL-52 virus, which was found in Laos, whose genome matches the genome of SARS Cove-2 by 96.8 percent. Similarly, the RaTG13 virus was found in Yuan, China, which matched 96.1 percent. The three to four percent genome differences from SARS Cove-2 suggest that the common ancestor of these viruses would be around 40 to 70 years old. (Representational photo: Shutterstock)

According to the study presented at the World One Health Congress in Singapore on 8 November, the role of recombination in the emergence of viruses is ignored by comparing the whole genome. In this process, viruses change some RNA among themselves. 18 By comparing the relatives of the coronavirus SARS-CoV-2 from bats and pangolins, and due to their different evolutionary histories, scientists were able to find that some parts share a common ancestor with the new coronavirus, which is only a few years old. were staying (Representational photo: Shutterstock)
Most of the virus had a common ancestor of the year 2007, but a small 250-nucleotide-long part had an ancestor of 2016 while the other 550-nucleotide-long part had an ancestor of 2015. Since the youngest parts were taken from bats in Yunnan and Laos, southern China, and Southeast Asia, they can be said to be the oldest ancestors of Sarskov-2 (SARS-CoV-2). (Representational photo: Shutterstock)

Unfortunately, these results reduce the time between the origin of the progenitor of SARS-CoV-2 in bats and its spread to humans. But still, it is not clear how this virus would have reached from the nearest ancestor animals to other animals including humans. This also indicates that some other animal may also have a role in it, about which information has not been found yet. (Representational photo: Shutterstock)

According to renowned virologist Edward Holmes of Australia’s University of Sydney, it is known how many times the coronavirus was found in you and how much it was found. The possibility will increase that we will never be able to find the closest ancestor of SARS Cove-2 (SARS-CoV-2) because the car has left. (Representational photo: Shutterstock)


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