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COVID-19: Nasal vaccine cannot be administered after booster dose, but why? 

The use of the India Nasal Vaccine has been approved. But doctors say that it would not be right to take it after a booster dose or precautionary dose. But yes it can be taken as a booster dose first. Experts say that the reason behind this will be the effectiveness of the previous dose of the vaccine and the ability of the body to be affected by repeated resistance. 

Experts say that there is no point in taking the Nasal Vaccine after the booster dose. (Pic: Twitter)

  • The nasal vaccine has been approved by the Ministry of Health in India.
  • iNCOVACC Nasal Vaccine can be used as the first booster dose.
  • Doctors say that it cannot be taken after a booster or precautionary dose.

The government is preparing seriously to deal with the apprehensions of the fourth wave of Covid-19 in India. At present, there is no such thing as danger in the country, but full arrangements are being made to take precautions so that the country does not have to go through past experiences. Meanwhile, there are also reports of Nasal Vaccines coming into the market. But it is necessary to have clear information on how it should be taken and when not so that further misconceptions and rumors can be avoided. The nasal vaccine can be taken as the first booster dose, but it should not be taken after the booster dose has already been taken. 

Same as the first booster dose only
A few days ago, a nasal vaccine named Incovac has been introduced on the Covin platform of the Government of India. Kovid Task Force chief NK Arora says that if someone has taken a booster dose or has taken a pre-precaution dose, then the nasal vaccine cannot be applied after that, but it can definitely be applied like a booster dose first.
No need for a fourth dose
At present, there is no provision for a fourth dose in the Covin vaccination program and this means that there is nothing like a recommendation or provision to take the nasal vaccine after three doses. Dr. Arora says that even if it is assumed that someone wants to take the fourth dose, then it is important to understand why it is not recommended. 
Concept of Andigen Sync
A concept that works behind this is called antigen sink. If a person repeatedly becomes immune to a particular type of antigen, then his body stops responding to it or starts giving a weak response. This is the reason why initially a gap of six months was imposed between mRNA vaccines. 
Benefits of giving by mouth or nose
Dr. Arora told the media that later the gap between the two doses was made three months for the people, but it did not help much. That’s why there is no importance of the fourth dose at this time. The nasal vaccine is given through the nose or mouth and it acts on the mucosal lining so that the nasal vaccine elicits an immediate immune response only at the entry point of the virus, which is usually the nose and mouth. 
It is advised not to give Nasal Vaccine after the booster dose. (file photo)
Shows fast effect
The special thing about the nasal vaccine is that it is said to act immediately and reduce the chances of spreading the infection immediately and many studies have also confirmed that it gives a very strong immune response. At present, the government has approved a novel adenovirus vector, an intralesional vaccine named Incovacc manufactured by Bharat Biotech.
A nasal Vaccine is considered better than an injectable vaccine. (file photo)
More profitable
It has been found that the nasal vaccine is more beneficial than the vaccine given by injection. In the third phase of its clinical trial, this vaccine was tried on three thousand participants, in which two doses at a gap of four weeks showed good results. The intramucosal vaccine works on the respiratory tract in which the vaccine works by finding and neutralizing or eliminating the virus.
Apart from India, China has also approved needle-free vaccines. China’s nasal vaccine has been developed by a company named Cansino Biologics of Tianjin and it is being used as a booster dose in China. At the same time, in India, the nasal vaccine has been approved as two primary doses instead of boosters.




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